Preparation of Compounds Labeled with Tritium and Carbon-14

Preparation of Compounds Labeled with Tritium and Carbon-14
Rolf Voges,J. Richard Heys,Thomas Moenius | 2009-06-02 00:00:00 | Wiley | 682 | Biochemistry
Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals.

Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures.  Topics include:

•  Formulation of synthetic strategies for preparing labeled compounds
• Isotope exchange methods and synthetic alternatives for preparing tritiated compounds
• In-depth discussion of carbon-14 building blocks and their utility in synthesis
• Preparation of enantiomerically pure isotopically labeled compounds
• Applications of biotransformations

Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.

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Techniques in Glycobiology

Techniques in Glycobiology
R. Reid Townsend,Arland T. Hotchkiss | 1997-06-25 00:00:00 | CRC Press | 648 | Biochemistry
This excellent reference covers state-of-the-art methodologies for plant and animal glycoconjugate analysis;detailing mass spectrometry, nuclear magnetic resonance spectroscopy, glycolipids and new physical methods, O-glycosylation characterization, chromophore and fluorophore labeling of oligosaccharides, separations, exoglycosidases and mapping, and plant glycobiology.

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Green Fluorescent Protein: Applications & Protocols (Methods in Molecular Biology)

Green Fluorescent Protein: Applications & Protocols (Methods in Molecular Biology)
Barry W. Hicks | 2002-06-01 00:00:00 | Humana Press | 408 | Biochemistry
Barry W. Hicks and a team of well-practiced experimentalists demonstrate the power and the versatility of the green fluorescent protein (GFP) marker with a cutting-edge collection of readily reproducible GFP techniques. These include methods for detecting and imaging GFP (FRET, BRET, and whole-body imaging); for using GFP to create and select for transgenic organisms, for its use as a biosensor; and for studying viruses. A valuable companion CD-ROM displays many color figures and videos from over half the chapters.

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Biophysical Techniques in Photosynthesis: Volume II (Advances in Photosynthesis and Respiration)

Biophysical Techniques in Photosynthesis: Volume II (Advances in Photosynthesis and Respiration)
Thijs J. Aartsma | 2008-03-11 00:00:00 | Springer | 520 | Biochemistry

Since the first volume on Biophysical Techniques in Photosynthesis Research, published in 1996, new experimental techniques and methods have been devised at a rapid pace. The present book is a sequel which complements the first volume by providing a comprehensive overview of the most important new techniques developed over the past ten years, especially those that are relevant for research on the mechanism and fundamental aspects of photosynthesis.

The contributions are written by leading scientists in their field. The book is divided into 5 sections on Imaging, Structure, Optical and laser spectroscopy, Magnetic resonance and on Theory, respectively. Each chapter describes the basic concepts of the technique, practical applications and some of the scientific results. Possibilities and limitations from a technical as well as a scientific point of view are addressed, allowing the reader not only to recognize the potential of a particular method for his/her own quest, but to assess the resources that are required for implementation.

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Functional Organization of the Plant Nucleus (Plant Cell Monographs)

Functional Organization of the Plant Nucleus (Plant Cell Monographs)
Iris Meier | 2008-11-27 00:00:00 | Springer | 192 | Biochemistry

While the cell nucleus was first identified in a plant, we know now far less about the plant nucleus than we know about its equivalent in animals or in fungi, because the field of nuclear biology has been predominantly driven by the non-plant model systems. More recently, however, plant biology has begun to catch up as research groups worldwide actively address the processes that define the plant nucleus. This volume is an up-to-date compilation of the multiple facets of this emerging discipline and presents the timely topic of functional organization of the cell nucleus entirely from the plant biologist s perspective. In a time of soaring food, fibre and energy needs, the understanding of the molecular mechanisms of plant genetic organization and its effect on plant growth and development - is essential.

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Protein Protocols Handbook (Methods in Molecular Biology)

Protein Protocols Handbook (Methods in Molecular Biology)
John M. Walker | 2002-04-15 00:00:00 | Humana Press | 1176 | Biochemistry
Univ. of Hertfordshire, Hatfield, UK. Provides a cross-section of analytical techniques commonly used for proteins and peptides. Each chapter opens with a description of the basic theory behind the method being described. Outline format. Previous edition: c1996. Hardcover, softcover also available.

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2 Volume Set, Human Protein Data

2 Volume Set, Human Protein Data
Edited by: Andre Haeberli | 1999-04-08 00:00:00 | Wiley-VCH | 1000 | Biochemistry
Human Protein Data is a unique compilation of data on the most important and best studied human proteins. This two volume set contains a total of about 314 detailed data sheets. The contents corresponds to the up-dated collection of data sheets of Installments 1 to 6 of the loose-leaf edition.
The points covered per individual protein far exceed those found in typical protein databases and include
biological functions/ physiology/ pathology/ degradation/ genetics/ abnormalities/ half-life/ concentration/isolation method
A computer retrievel program on disc permits easy searches trough the complete set of data. In addition to this a list of all contributors with their complete and up-to-date adresses provides the user with a Who is Who of modern protein research. Human Protein Data as an unique and indispensable reference work adds new and valuable dimensions to electronic database searches.

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Laboratory Techniques in Biochemistry and Molecular Biology: Isoelectric Focusing - Therory, Methodology and Applications Vol 11 (Laboratory Techniques in Biochemistry & Molecular Biology)

Laboratory Techniques in Biochemistry and Molecular Biology: Isoelectric Focusing - Therory, Methodology and Applications Vol 11 (Laboratory Techniques in Biochemistry & Molecular Biology)
Pier Giorgio Righetti | 1900-01-01 00:00:00 | Elsevier | 402 | Biochemistry

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Progress in Nucleic Acid Research and Molecular Biology, Volume 58

Progress in Nucleic Acid Research and Molecular Biology, Volume 58
Kivie Moldave | 1997-09-26 00:00:00 | Academic Press | 404 | Biochemistry
Praise for the Series
"In perusing these chapters, I found much of interest. It is worth investigating."
--P. Brickell in Biotechnology and Applied Biochemistry

"Full of interst not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."
--British Medical Journal


Key Features
* Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology
* Contributions from leaders in their fields
* Abundant references

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